Telomeres, Nutrition, and Longevity: Can We Really Control Aging?

Telomeres are dynamic structures at the ends of chromosomes and guardians of genomic stability. They are considered one of the main determinants of aging and lifespan in higher mammals. Research shows that there is a direct correlation between telomere length and life expectancy, stress, DNA damage, and the occurrence of age-related diseases. Various genetic and environmental factors such as diet, physical activity, obesity, and stress affect health and lifespan as well as telomere dynamics. Currently, there is an opportunity to regulate one's aging and healthspan by tracking telomere dynamics, monitoring these processes, and even predicting the future. Since telomeres respond to both positive and negative health factors, we should be able to directly affect telomere metabolism, slow their degradation, delay aging, and potentially extend lifespan and healthspan.